DIABETES (can-predict-10-year-earlier-by-a-blood-test)

REFERENCE
http://www.medic4health.com/2010/09/diabetes-can-predict-10-year-earlier-by-a-blood-test/

A blood test is developed by the scientists which can predict Diabetes 10 years Earlier. The researchers from Birmingham speaking at the British Science Festival that this test is specific for Type 2 Diabetes & can identify half of people who will develop Diabetes.The Test works by detecting levels of a genetic molecule (MiR) in blood.


The same molecule, called a microRNAÂ or MiR could help pinpoint sufferers at high risk of heart related and artery diseases. The test can also help to distinguish between those who will and those who will not go on to develop some of the complications of diabetes caused by damage to blood vessels, such as stroke ,heart attack, and poor circulation. The Principle of test is based on less shed of MiR in blood. It is belive that one type of micro-RNA, known as MiR-126, protects blood vessels from damage. Healthy blood vessel cells are able to release substantial MiR-126 in to the blood stream. However, when they become damaged, they need to keep the MiR-126 for themselves and shed less in to the blood.

The lead scientist Dr Manuel Mayr, from King’s College London, said he expected the MiR test to be used in conjunction with conventional methods and cost will around £2. Dr Mayr sais, “It’s very important for doctors to define those diabetic patients that are at the highest risk of developing cardiovascular complications”.

The most important use and advantage of this test its that it directly assessed the damage diabetes was causing to blood vessels. It  allow doctors to begin early treatment with cholesterol and blood pressure lowering drugs and target it at those who are most likely to benefit. Early diagnosed and identified people with diabetes are particularly at risk of having a heart attack or stroke

Dr Mayr studied 822 adults aged between 40 and 79 living in northern Italy. Of the two types of diabetes, type 2, or adult onset, diabetes is much more common. Around five per cent of adults in England have diagnosed type 2 diabetes. A further three percent of men and two per cent of women aged over 35 may have undiagnosed type 2 diabetes. Â The risk of having a heart attack is between two and five times greater in people with diabetes. Around 15 per cent of heart attacks in western Europe are due to diabetes. The findings were published in the journal Circulation Research. Professor Jeremy Pearson, associate medical director at the British Heart Foundation, which funded the research, said: “This is important because right now there is no quick and simple way to monitor blood vessel health.

REFERENCE: http://www.medic4health.com/2010/09/diabetes-can-predict-10-year-earlier-by-a-blood-test/